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Technology Guide
DDN’s Technology Guides provide the information scientists need to get started with new instruments, methods, and services.
Each Technology Guide includes the following content pieces:
- An introduction to the technology, including the top factors that new customers should consider when introducing your technology into their labs
- A graphical overview of the technique
- A table listing the key resources and products
- A troubleshooting Q&A article based on an interview with a product expert
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guide
2024 Multisponsored Topics
Mass Spectrometry
A Technology Guide for TMT-based Proteomic Analysis
Tandem mass tags (TMT) are powerful tools for proteomics that rely on isobaric chemical tags with different mass-to-charge ratios for multiplexed sample analysis. This technique enables concurrent comparison of multiple conditions, providing insights into differential protein expression, post-translational modifications, and protein interactions within complex biological samples. This Technology Guide will explore the fundamental principles and applications of TMT and discuss the considerations and best practices for TMT experiments.
Genomics and Sequencing
A Technology Guide for Metagenomics
Microbiome studies rely on 16S ribosomal RNA sequencing to identify microbes in a particular population. But sometimes knowing the identity of a microbe is not enough. That’s where shotgun metagenomics steps in. Metagenomics reveals the genomic information of all organisms in a sample, giving scientists insight on how each organism functions within the group. This Technology Guide will explain how shotgun metagenomics works, introduce best practices, and provide expert advice on starting metagenomics studies.
Proteomics
A Technology Guide for Bottom-up Proteomics
Bottom-up proteomics helps scientists to identify proteins and characterize their amino acid sequences and post-translational modifications. The approach involves proteolytic digestion of proteins prior to mass spectrometry analysis. It has been instrumental in uncovering biomarkers and elucidating protein interactions. This Technology Guide will explore the principles, techniques, and applications of bottom-up proteomics.
3D Cell Culture
A Technology Guide for 3D Cell Culture
Cells exist in living organisms in complicated multidimensional structures occupied by other cell types, supported by layers of extracellular matrix, and vascularized by vessels. 3D cell culture offers the opportunity to model these dynamic in vivo architectures more closely, but for many scientists new to this area of research, getting started is not easy. This Technology Guide will break down the key considerations for starting a 3D cell culture experiment, introduce the tools and reagents necessary for success, and provide expert troubleshooting advice.
CRISPR
A Technology Guide for CRISPR-based Screens
CRISPR-based screening takes advantage of the CRISPR/Cas9 gene-editing system to identify genes that are critical for disease processes, potentially leading to the development of new therapeutic strategies. This Technology Guide will explain how CRISPR-based screens work and provide guidance on how to choose and implement the best CRISPR screen to meet experimental needs.
Feature Fold
Take your posters to the next level with DDN’s new Feature Folds.
These extra-large pull-out inserts feature a poster that spans two tabloid-sized pages, a full-page Q&A article featuring an expert on your technology, and an insert cover page featuring title art above your advertisement.
Readers won’t be able to resist pulling the inserts from the magazine and hanging them on their laboratory walls.
Explainer Articles
Ask and answer an important question for your clients with an explainer article. Each explainer breaks down a bigger picture question into smaller questions and provides a thorough answer written by scientists for scientists. Custom graphics bring the text to life and clear up even the most complicated subjects.
Sponsor an explainer article from our editorial calendar, or partner with us to create a custom one just for you!
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2024 Multisponsored Topics
Cancer
How Do Cancer Cells Become Resistant to Drugs?
Drug resistance is a major cause of cancer treatment failure. Although a treatment may be effective initially, cancer cells can adapt to the drug, develop resistance, and regrow. This Explainer Article will explore the various underlying mechanisms driving cancer drug resistance and how scientists plan to overcome and prevent resistance to enhance treatment effectiveness.
Immunology
What Are the Effects of Aging on the Immune System?
As individuals age, the immune system’s function decreases. This can make older individuals more susceptible to infections and diseases. This Explainer Article will explore the effects of aging on various immune cell types and how they influence the risk for multiple disorders.
Neuroscience
How Does the Gut Affect the Brain?
The gut-brain axis is a bidirectional communication system connecting the gut and the brain. It involves the vagus nerve, neurotransmitters, hormones, immune cells, and the gut microbiome, and influences brain function and mental health. This Explainer Article will explore the intricate network of the gut-brain axis and its implications in developing novel therapies for targeting gut and brain health.
Stem Cells
How Does Stem Cell Therapy Work?
Stem cell therapy represents a promising realm within regenerative medicine. This approach involves the transplantation of stem cells into patients, harnessing the unique ability of these cells to transform into a diverse range of specialized cell types. This Explainer Article will explore the science behind stem cell therapy, its versatile applications, and novel strategies to overcome the development challenges of stem-cell-based treatments.
Science Milestones
Science Milestones detail the fascinating key events leading up to fundamental advances in life science research. Select from the topics on our editorial calendar, which are available for sponsorship, or bring us your own topic. We’ll do the research and present our readers with insights into your key technologies, methods, or equipment in a format that they want to read.
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Select a key discovery, technique, or instrument, and we’ll tell the story!
2024 Multisponsored Topics
Vaccines
Preventing Cervical Cancer with the HPV Vaccine
This Science Milestone will detail the key moments in history that laid the landscape for the HPV vaccine, which is 90 percent effective at preventing HPV cancers, including cervical, vaginal, vulvar, anal, penile, and throat cancer.
Proteomics
Imaging Mass Cytometry: Visualizing Proteins at the Single Cell Level
Scientists use IMC to study the intricacies of cancer microenvironments and to dissect their complex interplay with the immune system. This Science Milestone will explore the key advancements that led to its development.
Cancer
Using Viruses to Treat Cancer
This Science Milestone will explore the history of oncolytic virus therapy, tracing back to early 20th-century observations of viral-induced tumor regression, progressing through genetic engineering and virology advancements that yielded targeted oncolytic viruses, and culminating in the clinical trials and 2015 FDA approval of T-Vec.
Cell Therapy
Bone Marrow Transplant
Bone marrow transplants have saved lives for nearly a century. This Science Milestone will trace the origins, development, and refinement of therapeutic hematopoietic stem cell transplants.
Posters
Sponsor a planned poster, or schedule your own!
Posters are perfect for showcasing a technique, highlighting a new product, explaining complex scientific concepts, or detailing a new method. Pair your poster with a lead generation or promotional program to maximize its reach.
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NEW IN 2024 VIDEO
Work with DDN to turn your poster into a video.
We’ll provide you with the final video file and host it on our website to attract even more attention to your poster.
2024 Multisponsored Topics
Cancer
PROTAC cancer therapy
Proteolysis targeting chimeric (PROTAC) technology allows researchers to tag specific proteins for degradation by the cell. PROTAC technology may overcome some of the shortcomings of traditional cancer drugs. This poster will introduce the mechanisms and applications of PROTACs in cancer therapy.
Immunology and Flow Cytometry
Flow Cytometry for Antibody Discovery
Approximately 20 percent of newly approved drugs are monoclonal antibodies. For many of these, flow cytometry played an important role in their development. Researchers rely on flow cytometry to identify the best antibody clones that bind to target antigens. This poster will detail the role of flow cytometry in antibody discovery.
Spatial Biology
Exploring Spatial Transcriptomics
There are several different spatial transcriptomics technologies available, including microdissection, in situ hybridization, in situ sequencing, and in situ capturing. This poster will provide an overview of cutting-edge spatial transcriptomics methods.
Proteomics
Uncovering Tumor Antigens
This poster will describe the approaches scientists take to uncover high-fidelity tumor antigens, such as next generation sequencing of the whole exome, transcriptome, proteome, and ligandome coupled with chromatography-mass spectrometry-based detection methods.
Gene Therapy
Gene Therapy for Organ Transplants
This poster will explore the use of gene therapy for improving organ transplant outcomes, including reducing the need for immunosuppression and using genetic vectors to improve organ quality before transplant.
Webinars
Explore the list of webinars we have planned for 2024 and support those that reach your customers. Alternatively, connect with us to develop a custom event tailored precisely to your needs.
Our 2024 multisponsored webinars focus on the following topics:
Machine Learning and Artificial Intelligence
AI-powered Drug Discovery
Artificial intelligence and machine learning streamline the drug discovery process, from drug design to early safety assessments. This webinar will feature ways such as identifying drug targets and predicting drug properties in which AI-based computational approaches facilitate all stages of drug discovery.
Immunology
Targeting Epithelial Immune Memory to Treat Reinfections
As the first line of defense for the body’s organs, epithelial cells learn from previous infections or exposures to allergens. In this webinar, experts will discuss how to target epithelial memory to fight infectious diseases.
Antibody Drugs
CRISPR-based screens for drug discovery
Bispecific antibodies offer a novel approach for targeting multiple antigens simultaneously and enhancing treatment precision across various diseases, including cancer and autoimmune disorders. In this webinar, experts will shed light on the most recent developments in bispecific antibody design, engineering, and application.
Proteomics
Predictive Biomarker Discovery
Proteomics approaches provide valuable information on the identities, expression levels, and modifications of proteins. Scientists use this information to identify biomarkers, assess disease prognosis, and identify potential responders for specific therapies. This webinar will explore proteomic approaches, such as mass spectrometry-based technologies and others, to identify biomarkers that can predict treatment outcomes for patients
with cancer, Alzheimer’s disease, and others.
Immunotherapy
Combining Immune Checkpoint Inhibitors with Oncolytic Viruses for Cancer Therapy
Immune checkpoint inhibitors activate the immune system against cancer cells, but not every patient responds to this type of therapy. Oncolytic viruses can kill cancer cells directly and make cancer cells respond to immune checkpoint inhibitors. This webinar will showcase recent advancements in this combination therapy for cancer and highlight the mechanisms that make it effective.
Cell Therapy
The Promise of CAR Macrophage Therapy
Macrophages in the tumor microenvironment play a crucial role in promoting angiogenesis, facilitating tumor invasion, and mediating immunosuppression. Given their ability to infiltrate solid tumors and interact with various cellular components in the tumor microenvironment, researchers explore the use of chimeric antigen receptor (CAR) modified macrophages as potential therapeutics against solid tumors. In this webinar, experts will discuss the unique advantages of using macrophages for CAR therapy and the latest developments in their clinical utility.
Tissue Engineering
3D Models of Neurodegenerative Disease
The lack of in vitro models that recapitulate neurodegenerative diseases has hindered new drug development for brain disorders. In recent years, there have been exciting developments in creating advanced 3D lab models that better mimic the brain’s environment. This webinar will explore recent progress in developing these 3D models, including neural organoids, neurospheroids, scaffold-based models, and 3D bioprinted models.
Autoimmune Disease
Why the Body Attacks Itself
Autoimmune diseases now account for the third largest disease class in the United States after cancer and heart disease. While autoimmune diseases occur when the body attacks itself, why this happens largely remains a mystery. In this webinar, experts will explore the various mechanisms that cause the body to attack its own tissues and how they use this knowledge to treat and possibly prevent autoimmune diseases.
Pharmacogenomics
Pharmacogenomics and Pain
Individual patients respond differently to the same pain medications. The same dose may result in inadequate pain control for one patient and overmedication and side effects for another. Researchers studying pharmacogenetics for pain management identify genes related to drug receptors, transporters, and metabolizing enzymes that may help explain these differences and develop more precision medicine-based approaches to pain management. This webinar will present the latest pharmacogenomics research for pain management drugs.
Infectious Disease
Pharmacogenomics and Pain
Infectious diseases such as pneumonia, malaria, and tuberculosis claim thousands of lives yearly around the world. Treatments for these diseases exist, but drug resistance is a problem that contributes to their spread. This webinar will explore recent advancements in understanding the mechanisms of infectious disease drug resistance and the latest strategies for overcoming them.
Multiomics
Catching Cancer in a Drop of Blood
Liquid biopsies offer disease monitoring by exploring diverse cancer-related components in the blood, such as circulating tumor DNA, circulating tumor cells, circulating tumor RNAs, tumor-associated proteins, and tumor-derived extracellular vesicles. By leveraging multiomics tools, researchers analyze various biomolecules and integrate genomics, transcriptomics, proteomics, and other -omics data, enabling early and precise cancer detection. This webinar will discuss the progress of multiomics-based liquid biopsies for cancer.
Diagnostics
Monitoring Circadian Stress Hormones
Disrupted stress hormones contribute to endocrine conditions, heart disease, obesity, and cancer. Measuring hormonal changes might be key to identifying and monitoring disease. This webinar will feature new approaches for high-resolution monitoring of stress hormones as a promising pathway to diagnosis.
Cell Therapy
Monitoring Circadian Stress Hormones
Cell therapies typically involve a tailored process of extracting a patient’s cells, genetically modifying them, and then returning them to the patient. Allogeneic cell therapies promise the potential to accelerate that process by using off-the-shelf cells donated by healthy individuals and engineered to reduce immunogenicity. This webinar will feature the latest research on off-the-shelf cell therapies for cancer using various immune cell types.
Microbiome Biomarkers
Exploring Disease Biomarkers in the Microbiome
The human microbiome modulates important metabolic and immune processes. It is a valuable source of biomarkers for various health conditions, disease states, and treatment responses. In recent years, scientists have used metagenomics tools to identify many bacteria and bacterial products that correlate with disease. This webinar will discuss the emerging role of the gut microbiome as a valuable source of biomarkers for disease diagnostics and precision medicine.
Genetic Engineering
Genome Editing for Neurological Disorders
Genome editing holds immense potential for addressing central nervous system (CNS) disorders by precisely modifying genetic elements that contribute to these conditions. This technique offers the opportunity to correct mutations, regulate gene expression, and develop innovative therapies tailored to complex diseases. In this webinar, experts will share their strategies for leveraging genome editing tools like CRISPR-Cas9 to target genetic factors associated with CNS disorders.
Custom Articles
Advertorials
Research Product Highlights
Research Paper Summaries
White Papers
Custom Articles
DDN’s custom advertorial offerings are unique in the industry. We will tell your story and spread your message in a narrative engaging style that matches our various print content types. Select from a news story, a Q&A profile article, a traditional advertorial, or another article type that resonates with you.
The research product highlights section of our website gives readers quick, digestible information about tools and reagents that help advance science. Simply choose a product you would like to highlight, and we’ll do the rest.
Would you like to bring attention to key discoveries made using your products? Bring us a peer-reviewed paper, and we’ll create a research paper summary that presents the key methods and results in an accessible and engaging style.
We’ll work with you to provide all of the information necessary for your potential customers to make informed decisions about the tools and reagents they need to purchase for their upcoming experiments in a custom white paper.
We’ll talk with you to understand your goals, messaging, and audience, and then create just the content you need to educate your customers.
In this new podcast series, we cover the latest advancements in drug discovery by speaking directly with the scientists leading the efforts. Sponsor an episode from our 2024 calendar!
January
February
March
April
May
June
Metabolism
Genomics
Women's Health
Cancer
Ophthalmology
Microbiology
July
August
September
October
November
December
Cardiology
Infectious Disease
Machine Learning and AI
Gene Therapy
Neuroscience
Antibody Drugs
We’ll speak with your product managers, customers, or key opinion leaders to update our audience on the latest and greatest scientific technologies, products, and breakthroughs. Our podcast products begin with a kickoff call. We’ll take it from there to conduct the interview, prepare the script and audio files, and promote the podcast to our audience!
